Assessing the association of leukocyte telomere length with ankylosing spondylitis and rheumatoid arthritis: A bidirectional Mendelian randomization study

BackgroundTelomere length shortening can cause senescence and apoptosis in various immune cells, resulting in immune destabilization and ageing of the organism. In this study, we aimed to systematically assess the causal relationship of leukocyte telomere length (LTL) with ankylosing spondylitis (AS...

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Principais autores:	Donglei Wei, Yage Jiang, Jianwen Cheng, Hui Wang, Ke Sha, Jinmin Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-03-01
Colecção:	Frontiers in Immunology
Assuntos:	leukocyte telomere length ankylosing spondylitis rheumatoid arthritis Mendelian randomization single nucleotide polymorphism
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1023991/full
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