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Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy

Nucleotides are synthesized through two distinct pathways: de novo synthesis and nucleoside salvage. Whereas the de novo pathway synthesizes nucleotides from amino acids and glucose, the salvage pathway recovers nucleosides or bases formed during DNA or RNA degradation. In contrast to high prolifera...

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Détails bibliographiques
Auteurs principaux: Melanie Walter, Patrick Herr
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2022-02-01
Collection:Cells
Sujets:
Accès en ligne:https://www.mdpi.com/2073-4409/11/4/739
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