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Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy

Nucleotides are synthesized through two distinct pathways: de novo synthesis and nucleoside salvage. Whereas the de novo pathway synthesizes nucleotides from amino acids and glucose, the salvage pathway recovers nucleosides or bases formed during DNA or RNA degradation. In contrast to high prolifera...

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Autori principali: Melanie Walter, Patrick Herr
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-02-01
Serie:Cells
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Accesso online:https://www.mdpi.com/2073-4409/11/4/739
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