The effects of TGF-β-induced activation and starvation of vitamin A and palmitic acid on human stem cell-derived hepatic stellate cells

Abstract Background Hepatic stellate cells (HSC) have numerous critical roles in liver function and homeostasis, while they are also known for their importance during liver injury and fibrosis. There is therefore a need for relevant in vitro human HSC models to fill current knowledge gaps. In partic...

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Manylion Llyfryddiaeth

Prif Awduron:	Ingrid Wilhelmsen, Thomas Combriat, Andrea Dalmao-Fernandez, Justyna Stokowiec, Chencheng Wang, Petter Angell Olsen, Jonas Aakre Wik, Yuliia Boichuk, Aleksandra Aizenshtadt, Stefan Krauss
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2024-07-01
Cyfres:	Stem Cell Research & Therapy
Pynciau:	Hepatic stellate cells (HSC) Human pluripotent stem cells (hPSC) Fibrosis modeling In vitro Vitamin A Lipid droplets
Mynediad Ar-lein:	https://doi.org/10.1186/s13287-024-03852-8
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