The effects of TGF-β-induced activation and starvation of vitamin A and palmitic acid on human stem cell-derived hepatic stellate cells

Abstract Background Hepatic stellate cells (HSC) have numerous critical roles in liver function and homeostasis, while they are also known for their importance during liver injury and fibrosis. There is therefore a need for relevant in vitro human HSC models to fill current knowledge gaps. In partic...

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Detalhes bibliográficos

Principais autores:	Ingrid Wilhelmsen, Thomas Combriat, Andrea Dalmao-Fernandez, Justyna Stokowiec, Chencheng Wang, Petter Angell Olsen, Jonas Aakre Wik, Yuliia Boichuk, Aleksandra Aizenshtadt, Stefan Krauss
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-07-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Hepatic stellate cells (HSC) Human pluripotent stem cells (hPSC) Fibrosis modeling In vitro Vitamin A Lipid droplets
Acesso em linha:	https://doi.org/10.1186/s13287-024-03852-8
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