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Central and Peripheral Characterization of Key Kynurenine Pathway Metabolites in Mexican Patients with Multiple Sclerosis: An Exploratory Study

<b>Background/Objectives</b>: Multiple Sclerosis (MS) is a chronic immune-mediated disorder characterized by neuroinflammation and neurodegeneration. Increasing evidence implies the kynurenine pathway (KP) in the MS pathophysiology; however, data from Mexican populations are lacking. This explorator...

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Principais autores: Pablo Arturo Acosta Mendez, Graciela Ordoñez, Karla F. Meza-Sosa, Tonali Blanco Ayala, Daniela Ramirez Ortega, Gonzalo Pérez de la Cruz, Dinora F. González Esquivel, Teresita Corona, José Flores Rivera, Verónica Rivas, Paul Carrillo Mora, Carmen Aláez-Verson, Korrapati V. Sathyasaikumar, Saúl Gomez-Manzo, Aleli Salazar, Benjamin Pineda, Verónica Pérez de la Cruz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-03-01
coleção:Pharmaceuticals
Assuntos:
quinolinic acid
multiple sclerosis
kynurenine pathway
Acesso em linha:https://www.mdpi.com/1424-8247/19/3/513
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