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Long noncoding RNA MALAT1 regulates autophagy associated chemoresistance via miR-23b-3p sequestration in gastric cancer

Abstract Background Chemoresistance has long been recognized as a major obstacle in cancer therapy. Clarifying the underlying mechanism of chemoresistance would result in novel strategies to improve patient’s response to chemotherapeutics. Methods lncRNA expression levels in gastric cancer (GC) cell...

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Principais autores: Hu YiRen, Yu YingCong, You Sunwu, Li Keqin, Tong Xiaochun, Chen Senrui, Chen Ende, Lin XiZhou, Chen Yanfan
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-11-01
Serier:Molecular Cancer
Fag:
lncRNA
MALAT1
Gastric cancer
Chemoresistance
Autophagy
Online adgang:http://link.springer.com/article/10.1186/s12943-017-0743-3
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