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Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma

Abstract Background Acquired drug resistance is a constraining factor in clinical treatment of glioblastoma (GBM). However, the mechanisms of chemoresponsive tumors acquire therapeutic resistance remain poorly understood. Here, we aim to investigate whether temozolomide (TMZ) resistance of chemoresp...

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Bibliografiske detaljer
Principais autores: Zhuoran Zhang, Jianxing Yin, Chenfei Lu, Yutian Wei, Ailiang Zeng, Yongping You
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-04-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Online adgang:http://link.springer.com/article/10.1186/s13046-019-1139-6
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