Investigating the relationship of DNA methylation with mutation rate and allele frequency in the human genome
<p>Abstract</p> <p>Background</p> <p>DNA methylation, which mainly occurs at CpG dinucleotides, is a dynamic epigenetic regulation mechanism in most eukaryotic genomes. It is already known that methylated CpG dinucleotides can lead to a high rate of C to T mutation at these sites. However, less is k...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2012-12-01
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| coleção: | BMC Genomics |
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