Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis.

BACKGROUND:Thrombin activatable fibrinolysis inhibitor (TAFI), encoded by the Carboxypeptidase B2 gene (CPB2), is an inhibitor of fibrinolysis and plays a role in the pathogenesis of venous thrombosis. Experimental findings support a functional role of genetic variants in CPB2, while epidemiological...

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Главные авторы:	Nora Zwingerman, Alejandra Medina-Rivera, Irfahan Kassam, Michael D Wilson, Pierre-Emmanuel Morange, David-Alexandre Trégouët, France Gagnon
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2017-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC5446132?pdf=render
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