Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells
Summary: Hematopoietic stem cells (HSCs) generating all blood cells are maintained by their niche cells, termed CXCL12-abundant reticular (CAR) cells, which strongly overlap with leptin-receptor-expressing (LepR+) cells in the bone marrow. A meta-analysis of single-cell RNA sequencing datasets acros...
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| Principais autores: | , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Elsevier
2025-05-01
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| 丛编: | Cell Reports |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S2211124725003912 |
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