Evolutionary relaxation and functional change of INSL3 and RXFP2 may underlie natural cryptorchidism in mammals

Abstract Cryptorchidism is a common congenital abnormality that increases infertility and testicular cancer risk in adulthood. However, a few mammals exhibit naturally undescended testes while maintaining normal reproduction. The mechanisms underlying this natural cryptorchidism remain unclear. Here...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Yu Zheng, Simin Chai, Cuijuan Zhong, Yixuan Sun, Shixia Xu, Wenhua Ren, Guang Yang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer Nature 2025-11-01
Edice:	EMBO Reports
Témata:	Cryptorchidism INSL3 Gubernaculum Development Inflammation in Cryptorchid Testes Evolutionary Relaxation
On-line přístup:	https://doi.org/10.1038/s44319-025-00636-w
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!