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Uracil-DNA glycosylase of murine gammaherpesvirus 68 binds cognate viral replication factors independently of its catalytic residues

ABSTRACT Herpesviruses are large double-stranded DNA viruses that encode core replication proteins and accessory factors involved in nucleotide metabolism and DNA repair. Mammalian uracil-DNA glycosylases (UNG) excise deleterious uracil residues from their genomic DNA. Each herpesvirus UNG studied t...

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Hlavní autoři: Kyle R. Smith, Somnath Paul, Qiwen Dong, Orchi Anannya, Darby G. Oldenburg, J. Craig Forrest, Kevin M. McBride, Laurie T. Krug
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2023-10-01
Edice:mSphere
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On-line přístup:https://journals.asm.org/doi/10.1128/msphere.00278-23
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