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SIRT1-mediated deacetylation of DRP1 suppresses excessive mitophagy and ameliorates pediatric functional dyspepsia

Abstract Functional dyspepsia (FD) is a prevalent gastrointestinal disorder in children, but its underlying molecular mechanisms remain poorly understood. Mitochondrial dysfunction and excessive mitophagy have been implicated in FD, but the underlying mechanisms remain poorly understood. This study...

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主要な著者: Shuan Yin, Dongdong Dai, Gaoyan Wang, Shaomei Zhou
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2026-05-01
シリーズ:BMC Immunology
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オンライン・アクセス:https://doi.org/10.1186/s12865-026-00842-8
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