Enhancing gastric cancer conventional chemotherapy effects by triple angiokinase inhibitor nintedanib in preclinical models

BackgroundGastric adenocarcinoma (GAC) is the fourth leading cause of cancer death worldwide. Systemic chemotherapy is a preferred treatment option for advanced and recurrent GAC, but response rates and survival prolongation remain limited. Tumor angiogenesis plays a critical role in GAC growth, inv...

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Detalhes bibliográficos

Principais autores:	Niranjan Awasthi, Margaret A. Schwarz, Quinn Kaurich, Changhua Zhang, Frank Hilberg, Roderich E. Schwarz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-05-01
coleção:	Frontiers in Oncology
Assuntos:	gastric cancer chemotherapy nintedanib angiogenesis combination therapy
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1145999/full
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