Multicenter dose de-escalation phase I trial of pressurized intraperitoneal aerosolized chemotherapy (PIPAC) nab-paclitaxel and cisplatin in combination with systemic nab-paclitaxel in recurrent ovarian cancer patients: trial in progress

Ovarian cancer (OC) often presents with peritoneal metastases (PM) which contribute significantly to morbidity and treatment resistance. Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) has emerged as a promising modality for locoregional drug delivery in peritoneal surface malignancies....

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Hauptverfasser:	Popat Vinita, Frankel Paul H., Ruel Nora H., Yost Susan E., Chang Sue, Wang Edward, Villella Jeannine, Whyte Jill, Whelan Richard L., Eng Melissa, Tinsley Raechelle, Synold Tim, Han Ernest, Song Mihae, Cohen Joshua, Raoof Mustafa, Dellinger Thanh Hue
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	De Gruyter 2025-12-01
Schriftenreihe:	Pleura and Peritoneum
Schlagworte:	ovarian cancer phase i trial pipac nab-paclitaxel multimodal therapy
Online-Zugang:	https://doi.org/10.1515/pp-2025-0036
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