GPCR Conformations: Implications for Rational Drug Design
G protein-coupled receptors (GPCRs) comprise a large class of transmembrane proteins that play critical roles in both normal physiology and pathophysiology. These critical roles offer targets for therapeutic intervention, as exemplified by the substantial fraction of current pharmaceutical agents th...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2010-12-01
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| coleção: | Pharmaceuticals |
| Assuntos: | |
| Acesso em linha: | http://www.mdpi.com/1424-8247/4/1/7/ |
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