Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System

Fusobacterium nucleatum is a common oral bacterium that is enriched in colorectal adenomas and adenocarcinomas (CRC). In humans, high fusobacterial CRC abundance is associated with chemoresistance and poor prognosis. In animal models, fusobacteria accelerate CRC progression. Targeting F. nucleatum m...

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Autors principals:	Jawad Abed, Naseem Maalouf, Abigail L. Manson, Ashlee M. Earl, Lishay Parhi, Johanna E. M. Emgård, Michael Klutstein, Shay Tayeb, Gideon Almogy, Karine A. Atlan, Stella Chaushu, Eran Israeli, Ofer Mandelboim, Wendy S. Garrett, Gilad Bachrach
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-08-01
Col·lecció:	Frontiers in Cellular and Infection Microbiology
Matèries:	CRC (colorectal cancer) Fusobacterium nucleatum transient bacteremia oral microbes cancer
Accés en línia:	https://www.frontiersin.org/article/10.3389/fcimb.2020.00400/full
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