A modular dual-siRNA delivery platform based on GalNAc and click chemistry for multigene targeting
Small interfering RNA (siRNA) therapeutics offer considerable promise due to their gene-specific mechanism of action via Watson–Crick base pairing. While GalNAc–siRNA conjugation has demonstrated success in liver-targeted therapies, addressing complex diseases such as cancer and cardiovascular disor...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2025-11-01
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| Serie: | Results in Chemistry |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2211715625006757 |
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