In crystallo observation of three metal ion promoted DNA polymerase misincorporation
By observing DNA polymerase misincorporation with time-resolved crystallography, the authors visualize three-metal ion dependent polymerase catalysis and identify A-site metal-mediated primer alignment as a key step in nucleotide discrimination.
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Portfolio
2022-04-01
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| Saila: | Nature Communications |
| Sarrera elektronikoa: | https://doi.org/10.1038/s41467-022-30005-3 |
| Etiketak: |
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