In crystallo observation of three metal ion promoted DNA polymerase misincorporation
By observing DNA polymerase misincorporation with time-resolved crystallography, the authors visualize three-metal ion dependent polymerase catalysis and identify A-site metal-mediated primer alignment as a key step in nucleotide discrimination.
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Portfolio
2022-04-01
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| Sarja: | Nature Communications |
| Linkit: | https://doi.org/10.1038/s41467-022-30005-3 |
| Tagit: |
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