Comprehensive computational analysis of PKCδ non-synonymous variants identifies rs1703863535 as a potential breast cancer biomarker

Abstract PKCδ is a key isoform in the PKC subgroup of AGC-kinase proteins, known to be involved in various cellular processes. Dysregulation of its expression has been linked to multiple malignancies. Notably, PKCδ overexpression has been associated with breast cancer progression and poor prognosis....

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Manylion Llyfryddiaeth

Prif Awduron:	Sameen Zafar, Yasmin Badshah, Maria Shabbir, Somia Khan, Amna Hafeez, Naeem Mahmood Ashraf, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal, Suhail Razak
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2025-10-01
Cyfres:	BMC Cancer
Pynciau:	Cancer PKC Single Nucleotide Polymorphisms oncogene
Mynediad Ar-lein:	https://doi.org/10.1186/s12885-025-15194-6
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