Comprehensive analysis of gene expression alterations in breast cancer patients via PKCθ-TBK1-mTORC1 signaling pathway

Abstract Background Breast cancer remains a leading cause of cancer-related mortality among women globally. The emergence of chemoresistance and the lack of early detection tools necessitate the identification of reliable molecular biomarkers and therapeutic targets. Protein kinase C theta (PRKCQ/PK...

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Главные авторы:	Amna Hafeez, Mahnoor Basit, Sameen Zafar, Maria Shabbir, Yasmin Badshah, Janeen H. Trembley, Tayyaba Afsar, Altaf Khan, Suhail Razak
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2025-11-01
Серии:	BMC Cancer
Предметы:	Cancer PRKCQ Biomarkers Molecular Docking Breast cancer
Online-ссылка:	https://doi.org/10.1186/s12885-025-15352-w
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