Isosterism and Bioisosterism Case Studies with Muscarinic Agonists
The synthesis and activity of enantiomerically pure analogues of pilocarpine and muscarinic agonists with the azabicyclo[2.2.1]heptane skeleton is described. Structure-activity relationships support a flexible model in which a coulombic interaction as well as two H-bonding interactions wit...
Kaydedildi:
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Alemão |
| Baskı/Yayın Bilgisi: |
Swiss Chemical Society
1992-07-01
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| Seri Bilgileri: | CHIMIA |
| Online Erişim: | https://www.chimia.ch/chimia/article/view/2154 |
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