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Multitargeting nature of muscarinic orthosteric agonists and antagonists

Muscarinic receptors (mAChRs) are typical members of the G protein-coupled receptor (GPCR) family and exist in five subtypes from M1 to M5. Muscarinic receptor subtypes do not sufficiently differ in affinity to orthosteric antagonists or agonists; therefore, the analysis of receptor subtypes is comp...

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Bibliografiske detaljer
Hovedforfatter: Jaromir Myslivecek
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-09-01
Serier:Frontiers in Physiology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fphys.2022.974160/full
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