The dual-site agonist for human M2 muscarinic receptors Iper-8-naphtalimide induces mitochondrial dysfunction in Saccharomyces cerevisiae

Glioblastoma is a malignant astrocytic tumor of the brain. A significantly decrease of glioblastoma cell proliferation and survival can be achieved by activating the M2 muscarinic acetylcholine receptor (a G protein-coupled receptor, or GPCR) with two agonist molecules, the orthosteric agonist Areca...

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Prif Awduron:	Angela Cirigliano, Antonia Amelina, Elena Passarini, Alessandra Ricelli, Nicole Balasco, Mattia Mori, Bruno Botta, Maria Egle De Stefano, Claudio Papotto, Claudia Guerriero, Ada Maria Tata, Teresa Rinaldi
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Shared Science Publishers OG 2025-12-01
Cyfres:	Microbial Cell
Pynciau:	glioblastoma m2 muscarinic receptor orthosteric agonist dualsteric agonist ergosterol mitochondrial dna modeling in s. cerevisiae
Mynediad Ar-lein:	http://microbialcell.com/researcharticles/2025a-cirigliano-microbial-cell
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