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Endothelial glycocalyx injury is involved in heatstroke-associated coagulopathy and protected by N-acetylcysteine

IntroductionDamage to endothelial glycocalyx (EGCX) can lead to coagulation disorders in sepsis. Heat stroke (HS) resembles sepsis in many aspects; however, it is unclear whether EGCX injury is involved in its pathophysiology. The purpose of this study was to examine the relationship between the dam...

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Principais autores: Na Peng, Yan Geng, Jiafu Ouyang, Shuai Liu, Fangfang Yuan, Yantong Wan, Wenda Chen, Baojun Yu, Youqing Tang, Lei Su, Huaping Liang, Jiang Huai Wang, Jinghua Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-06-01
coleção:Frontiers in Immunology
Assuntos:
coagulopathy
endothelial glycocalyx
heat stroke
hyaluronic acid
N-acetylcysteine
syndecan-1
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1159195/full
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