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Systemic endothelial glycocalyx shedding mediates vascular hyperpermeability after traumatic brain injury

BackgroundIn traumatic brain injury (TBI), the primary insult initiates a secondary cascade that exacerbates neuronal injury. Blood–brain barrier (BBB) dysfunction plays a central role in this process, leading to vascular leakage and vasogenic edema. Recent evidence suggests that the endothelial gly...

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Principais autores: Marcela Curci Vieira de Almeida, Maria Clara Zanon Zotin, Carlos Henrique Miranda
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2026-01-01
Serija:Frontiers in Neurology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fneur.2025.1706102/full
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