Lung microbiota-derived deoxyinosine alleviates TBI-aggravated sepsis-induced lung injury via the S100A9/RAGE pathway

Abstract Traumatic brain injury (TBI) frequently leads to severe systemic complications, with pulmonary dysfunction acting as a major determinant of poor prognosis in survivors. While the lung microbiota is increasingly recognized as a critical regulator of pulmonary immune homeostasis, the specific...

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Prif Awduron:	Bailun Wang, Angran Gu, Yizheng Yang, Xuan Liu, Runmeng Liu, Yuelan Wang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2026-05-01
Cyfres:	Journal of Neuroinflammation
Pynciau:	Brain-Lung Axis Traumatic Brain Injury Lung Microbiota S100A9/RAGE Pathway Macrophage Polarization
Mynediad Ar-lein:	https://doi.org/10.1186/s12974-026-03862-8
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