Macrophages from naked mole-rat possess distinct immunometabolic signatures upon polarization

The naked mole-rat (NMR) is a unique long-lived rodent which is highly resistant to age-associated disorders and cancer. The immune system of NMR possesses a distinct cellular composition with the prevalence of myeloid cells. Thus, the detailed phenotypical and functional assessment of NMR myeloid c...

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Hlavní autoři:	Ekaterina A. Gorshkova, Ekaterina O. Gubernatorova, Ekaterina M. Dvorianinova, Taisiya R. Yurakova, Maria V. Marey, Olga A. Averina, Susanne Holtze, Thomas B. Hildebrandt, Alexey A. Dmitriev, Marina S. Drutskaya, Mikhail Yu. Vyssokikh, Sergei A. Nedospasov
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-04-01
Edice:	Frontiers in Immunology
Témata:	naked mole-rat macrophage polarization inducible NO-synthase immunometabolism
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172467/full
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