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Macrophages from naked mole-rat possess distinct immunometabolic signatures upon polarization

The naked mole-rat (NMR) is a unique long-lived rodent which is highly resistant to age-associated disorders and cancer. The immune system of NMR possesses a distinct cellular composition with the prevalence of myeloid cells. Thus, the detailed phenotypical and functional assessment of NMR myeloid c...

Deskribapen osoa

Gorde:
Egile Nagusiak: Ekaterina A. Gorshkova, Ekaterina O. Gubernatorova, Ekaterina M. Dvorianinova, Taisiya R. Yurakova, Maria V. Marey, Olga A. Averina, Susanne Holtze, Thomas B. Hildebrandt, Alexey A. Dmitriev, Marina S. Drutskaya, Mikhail Yu. Vyssokikh, Sergei A. Nedospasov
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2023-04-01
Saila:Frontiers in Immunology
Gaiak:
naked mole-rat
macrophage
polarization
inducible NO-synthase
immunometabolism
Sarrera elektronikoa:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172467/full
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