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The osteocytic actions of glucocorticoids on bone mass, mechanical properties, or perilacunar remodeling outcomes are not rescued by PTH(1-34)

Glucocorticoids (GC) and parathyroid hormone (PTH) are widely used therapeutic endocrine hormones where their effects on bone and joint arise from actions on multiple skeletal cell types. In osteocytes, GC and PTH exert opposing effects on perilacunar canalicular remodeling (PLR). Suppressed PLR can...

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Principais autores: Cristal S. Yee, Christoforos Meliadis, Serra Kaya, Wenhan Chang, Tamara Alliston
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2024-07-01
叢編:Frontiers in Endocrinology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fendo.2024.1342938/full
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