The osteocytic actions of glucocorticoids on bone mass, mechanical properties, or perilacunar remodeling outcomes are not rescued by PTH(1-34)

Glucocorticoids (GC) and parathyroid hormone (PTH) are widely used therapeutic endocrine hormones where their effects on bone and joint arise from actions on multiple skeletal cell types. In osteocytes, GC and PTH exert opposing effects on perilacunar canalicular remodeling (PLR). Suppressed PLR can...

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Главные авторы:	Cristal S. Yee, Christoforos Meliadis, Serra Kaya, Wenhan Chang, Tamara Alliston
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2024-07-01
Серии:	Frontiers in Endocrinology
Предметы:	osteocyte glucocorticoids prednisolone parathyroid hormone (PTH) PTH (1-34) perilacunar canalicular remodeling
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1342938/full
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