CREB Drives Acinar to Ductal Cells Reprogramming and Promotes Pancreatic Cancer Progression in Preclinical Models of Alcoholic PancreatitisSummary

Background & Aims: Chronic alcoholism often leads to pancreatitis, which exacerbates pancreatic damage through acinar cell injury and fibrotic inflammation activating AKT/mTOR/cyclic adenosine monophosphate response element binding protein 1 (CREB) signaling axis. However, the molecular interpla...

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Bibliografiske detaljer

Principais autores:	Supriya Srinivasan, Siddharth Mehra, Sudhakar Jinka, Anna Bianchi, Samara Singh, Austin R. Dosch, Haleh Amirian, Varunkumar Krishnamoorthy, Iago De Castro Silva, Manan Patel, Edmond Worley III. Box, Vanessa Garrido, Tulasigeri M. Totiger, Zhiqun Zhou, Yuguang Ban, Jashodeep Datta, Michael VanSaun, Nipun Merchant, Nagaraj S. Nagathihalli
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2025-01-01
Serier:	Cellular and Molecular Gastroenterology and Hepatology
Fag:	Acinar-To-Ductal Metaplasia Alcoholic Chronic Pancreatitis cAMP Response Element Binding Protein 1 Pancreatic Cancer Pancreatic Ductal Adenocarcinoma Pancreatic Intraepithelial Neoplasia
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2352345X2500147X
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