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Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicum

Abstract Background In the process of hepatic fibrosis, hepatic stellate cells (HSCs) can be activated by many inflammatory cytokines. The transforming growth factor-β1 (TGF-β1) is one of the main profibrogenic mediators. Recently, some studies have also shown that microRNAs (miRNAs) play essential...

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Hlavní autoři: Dandan Zhu, Xue He, Yinong Duan, Jinling Chen, Jianxin Wang, Xiaolei Sun, Hongyan Qian, Jinrong Feng, Wei Sun, Feifan Xu, Lingbo Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2014-03-01
Edice:Parasites & Vectors
Témata:
miR-454
TGF-β1
Hepatic stellate cell
Hepatic fibrosis
Schistosoma japonicum
On-line přístup:https://doi.org/10.1186/1756-3305-7-148
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