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MRGPRX2 Activation by Rocuronium: Insights from Studies with Human Skin Mast Cells and Missense Variants

Perioperative hypersensitivity (POH) to the neuromuscular blocking drug (NMBD) rocuronium was previously thought to be IgE and mast cell (MC)-mediated. However, the recent seminal observation that rocuronium induces degranulation in murine peritoneal MCs (PMCs) via Mas-related G protein-coupled rece...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Chalatip Chompunud Na Ayudhya, Aetas Amponnawarat, Saptarshi Roy, Carole A. Oskeritzian, Hydar Ali
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2021-01-01
Sraith:Cells
Ábhair:
Rochtain ar líne:https://www.mdpi.com/2073-4409/10/1/156
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