Aberrant spinal mechanical loading stress triggers intervertebral disc degeneration by inducing pyroptosis and nerve ingrowth

Abstract Aberrant mechanical factor is one of the etiologies of the intervertebral disc (IVD) degeneration (IVDD). However, the exact molecular mechanism of spinal mechanical loading stress-induced IVDD has yet to be elucidated due to a lack of an ideal and stable IVDD animal model. The present stud...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Fangda Fu, Ronghua Bao, Sai Yao, Chengcong Zhou, Huan Luo, Zhiguo Zhang, Huihao Zhang, Yan Li, Shuxin Yan, Huan Yu, Weibin Du, Yanping Yang, Hongting Jin, Peijian Tong, Zhi-tao Sun, Ming Yue, Di Chen, Chengliang Wu, Hongfeng Ruan
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Nature Portfolio 2021-01-01
سلاسل:	Scientific Reports
الوصول للمادة أونلاين:	https://doi.org/10.1038/s41598-020-80756-6
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!