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Microtubule stabilization promotes the synthesis of type 2 collagen in nucleus pulposus cell by activating hippo-yap pathway

Intervertebral disc degeneration (IDD) is the cardinal pathological mechanism that underlies low back pain. Mechanical stress of the intervertebral disc may result in a change in nucleus pulposus cells state, matrix degradation, and degeneration of the disc. Microtubules, which are components of the...

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Detaylı Bibliyografya
Asıl Yazarlar: Xin Zhang, Shibin Shu, Zhenhua Feng, Yong Qiu, Hongda Bao, Zezhang Zhu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2023-01-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fphar.2023.1102318/full
Etiketler: Etiketle
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