GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons

The molecular mechanism controlling the trafficking and function of AMPARs at synapses are not fully understood. Here the authors show that GSG1L, a membrane protein, negatively regulates AMPAR-mediated synaptic transmission and represents a new class of AMPAR auxiliary subunit.

Detalhes bibliográficos

Principais autores:	Xinglong Gu, Xia Mao, Marc P. Lussier, Mary Anne Hutchison, Liang Zhou, F. Kent Hamra, Katherine W. Roche, Wei Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2016-03-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/ncomms10873
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