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Regulated spindle orientation buffers tissue growth in the epidermis

Tissue homeostasis requires a balance between progenitor cell proliferation and loss. Mechanisms that maintain this robust balance are needed to avoid tissue loss or overgrowth. Here we demonstrate that regulation of spindle orientation/asymmetric cell divisions is one mechanism that is used to buff...

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Detalhes bibliográficos
Principais autores: Angel Morrow, Julie Underwood, Lindsey Seldin, Taylor Hinnant, Terry Lechler
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2019-10-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/48482
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