Identification and verification of SPP1 in anoikis as a prognostic biomarker for intestinal metaplasia and gastric cancer

Abstract Anoikis is a form of apoptosis induced by cell detachment from the extracellular matrix, and cancer cells must evade it to metastasize. Gastric cancer (GC) remains a leading global cause of cancer-related mortality, with intestinal metaplasia (IM) established as a key premalignant lesion. T...

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Hauptverfasser:	Kairui Wu, Yu Ye, Bei Pei, Biao Song, Yi Zhang, Tingting Li, Qi Yang, Yueping Jin, Hongliang Cheng, Xuejun Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-01-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Anoikis Gastric cancer Intestinal metaplasia SPP1 Correa cascade
Online-Zugang:	https://doi.org/10.1038/s41598-026-36714-9
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