Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis

BackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment. The objective of this study is to explore the mechanism of rabeprazole in gas...

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Autors principals:	Jing Xie, Xinhua Liang, Fangfang Xie, Canxin Huang, Zijun Lin, Shuping Xie, Fangying Yang, Fengfeng Zheng, Lanlan Geng, Wanfu Xu, Sitang Gong, Li Xiang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-11-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	H. pylori gastric intestinal metaplasia rabeprazole ferroptosis CREB
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1409001/full
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