Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer’s disease

Abstract Background A decline in instrumental activities of daily living (IADL) correlates with the progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD) dementia and has been associated with frontal and parietal hypometabolism, lower cerebrospinal fluid amyloid β 1–42, and in...

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Auteurs principaux:	Omar A. Halawa, Jennifer R. Gatchel, Rebecca E. Amariglio, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Gad A. Marshall, Alzheimer’s Disease Neuroimaging Initiative
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2019-01-01
Collection:	Alzheimer’s Research & Therapy
Sujets:	Alzheimer’s disease Instrumental activities of daily living Tau Amyloid Positron emission tomography Mild cognitive impairment
Accès en ligne:	http://link.springer.com/article/10.1186/s13195-019-0471-6
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