Inferior and medial temporal tau and cortical amyloid are associated with daily functional impairment in Alzheimer’s disease

Abstract Background A decline in instrumental activities of daily living (IADL) correlates with the progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD) dementia and has been associated with frontal and parietal hypometabolism, lower cerebrospinal fluid amyloid β 1–42, and in...

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Главные авторы:	Omar A. Halawa, Jennifer R. Gatchel, Rebecca E. Amariglio, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Gad A. Marshall, Alzheimer’s Disease Neuroimaging Initiative
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2019-01-01
Серии:	Alzheimer’s Research & Therapy
Предметы:	Alzheimer’s disease Instrumental activities of daily living Tau Amyloid Positron emission tomography Mild cognitive impairment
Online-ссылка:	http://link.springer.com/article/10.1186/s13195-019-0471-6
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