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Predictive role of plasmatic biomarkers in advanced non-small cell lung cancer treated by nivolumab

Immune checkpoint inhibitors, as nivolumab, are used in advanced non-small cell lung cancer (NSCLC). However, no associated biomarker is validated in clinical practice with this drug. We investigated herein immune-related blood markers in patients with advanced NSCLC treated with nivolumab. Plasma o...

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Principais autores: Adrien Costantini, Catherine Julie, Coraline Dumenil, Zofia Hélias-Rodzewicz, Julie Tisserand, Jennifer Dumoulin, Violaine Giraud, Sylvie Labrune, Thierry Chinet, Jean-François Emile, Etienne Giroux Leprieur
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2018-08-01
Serier:OncoImmunology
Fag:
nivolumab
non-small cell lung cancer
plasma
pd-l1
pd-l2
granzyme b
interleukine-2
interferon-γ
microrna
biomarker
Online adgang:http://dx.doi.org/10.1080/2162402X.2018.1452581
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