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Fission yeast Rad54 prevents intergenerational buildup of Rad51 aggregates in proliferating cells

Live imaging of Rad51 revealed that rad54 mutant cells not only accumulate Rad51 but also transmit Rad51 aggregates to daughter cells, which likely causes intergenerational genome instability. Homologous recombination is central to the maintenance of genome stability. Using fission yeast, we found t...

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Bibliografske podrobnosti
Principais autores: Goki Taniguchi, Alexander I May, Hiroshi Iwasaki, Hideo Tsubouchi
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2025-11-01
Serija:Life Science Alliance
Online dostop:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503252
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