Therapeutic Potential of PARP Inhibitors in the Treatment of Gastrointestinal Cancers

Gastrointestinal (GI) malignancies are a major global health burden, with high mortality rates. The identification of novel therapeutic strategies is crucial to improve treatment and survival of patients. The poly (ADP-ribose) polymerase (PARP) enzymes involved in the DNA damage response (DDR) play...

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Prif Awduron:	Abdullah Alhusaini, Aoife Cannon, Stephen G. Maher, John V. Reynolds, Niamh Lynam-Lennon
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2021-08-01
Cyfres:	Biomedicines
Pynciau:	PARP PARP inhibitors gastrointestinal cancers DNA damage response chemoradiotherapy resistance
Mynediad Ar-lein:	https://www.mdpi.com/2227-9059/9/8/1024
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!