Iron overload and impaired iron handling contribute to the dystrophic pathology in models of Duchenne muscular dystrophy

Abstract Background Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular dystrophies. To our knowledge, the distribution of iron, an important modulator of oxidative...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Francesca M. Alves, Kai Kysenius, Marissa K. Caldow, Justin P. Hardee, Jin D. Chung, Jennifer Trieu, Dominic J. Hare, Peter J. Crouch, Scott Ayton, Ashley I. Bush, Gordon S. Lynch, René Koopman
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2022-06-01
Reeks:	Journal of Cachexia, Sarcopenia and Muscle
Onderwerpen:	Muscular dystrophy Muscle metabolism Iron Oxidative stress
Online toegang:	https://doi.org/10.1002/jcsm.12950
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!