Iron overload and impaired iron handling contribute to the dystrophic pathology in models of Duchenne muscular dystrophy

Abstract Background Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular dystrophies. To our knowledge, the distribution of iron, an important modulator of oxidative...

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Bibliografiska uppgifter

Huvudupphov:	Francesca M. Alves, Kai Kysenius, Marissa K. Caldow, Justin P. Hardee, Jin D. Chung, Jennifer Trieu, Dominic J. Hare, Peter J. Crouch, Scott Ayton, Ashley I. Bush, Gordon S. Lynch, René Koopman
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Wiley 2022-06-01
Serie:	Journal of Cachexia, Sarcopenia and Muscle
Ämnen:	Muscular dystrophy Muscle metabolism Iron Oxidative stress
Länkar:	https://doi.org/10.1002/jcsm.12950
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