Microglia cause structural remodeling of noradrenergic axon in the trigeminal spinal subnucleus caudalis after infraorbital nerve injury in rats

The dysfunction of descending noradrenergic (NAergic) modulation in second-order neurons has long been observed in neuropathic pain. In clinical practice, antidepressants that increase noradrenaline levels in the synaptic cleft are used as first-line agents, although adequate analgesia has not been...

Descripció completa

Dades bibliogràfiques

Autors principals:	Yoshinori Hayashi, Jo Otsuji, Eri Oshima, Suzuro Hitomi, Junjun Ni, Kentaro Urata, Ikuko Shibuta, Koichi Iwata, Masamichi Shinoda
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-07-01
Col·lecció:	Brain, Behavior, & Immunity - Health
Matèries:	Exosomes Interferon-γ Locus coeruleus Major histocompatibility complex I Mechanical allodynia Microglia
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2666354623000364
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!